2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7516
    4'-Hydroxy-2,4-dimethoxychalcone
    		Inhibitor 99.76%
    4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity.
    4'-Hydroxy-2,4-dimethoxychalcone
  • HY-N2848
    α-Lapachone
    		99.65%
    α-Lapachone shows trypanocidal activity.
    α-Lapachone
  • HY-B0803S1
    Lumefantrine-d9
    		Inhibitor
    Lumefantrine-d9 is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.
    Lumefantrine-d<sub>9</sub>
  • HY-129051
    Amoscanate
    		99.45%
    Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma.
    Amoscanate
  • HY-W003561
    DHFR-IN-3
    		Inhibitor 99.64%
    DHFR-IN-3 is a dihydrofolate reductase (DHFR) inhibitor with the IC50 values of 19 μM and 12 μM in rat liver and P. carinii DHFR, respectively.
    DHFR-IN-3
  • HY-N7227
    Anonaine
    		Inhibitor
    Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor.
    Anonaine
  • HY-113715
    Niclofolan
    		Inhibitor 99.55%
    Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection.
    Niclofolan
  • HY-N3013
    Bruceine B
    		Inhibitor 99.60%
    Bruceine B inhibits protein synthesis and nucleic acid synthesis.
    Bruceine B
  • HY-66004
    4-Acetamidophenyl acetate
    4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic agent, is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    4-Acetamidophenyl acetate
  • HY-19285
    Sulfaclozine
    		Inhibitor ≥99.0%
    Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine
  • HY-B0497S1
    Niclosamide-13C6
    		Inhibitor ≥99.0%
    Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
    Niclosamide-<sup>13</sup>C<sub>6</sub>
  • HY-B0488
    Clorsulon
    		Inhibitor 99.99%
    Clorsulon (L631529; MK401) is an orally active flukicidal agent against liver flukes (Fasciola hepatica and Fasciola gigantica) infections in calves and sheep. Clorsulon is also a competitive inhibitor of both 3-phosphoglycorate and ATP andinhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro.
    Clorsulon
  • HY-118224
    BPH-715
    		Inhibitor 99.62%
    BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.
    BPH-715
  • HY-137445
    Modoflaner
    		Inhibitor 98.01%
    Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels.
    Modoflaner
  • HY-N5029
    Isofebrifugine
    		Inhibitor 98.90%
    Isofebrifugine is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect.
    Isofebrifugine
  • HY-N5018
    Nepodin
    		Inhibitor 99.71%
    Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities.
    Nepodin
  • HY-135847
    Desmethyl ferroquine
    		Inhibitor 98.02%
    Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains.
    Desmethyl ferroquine
  • HY-12082A
    GSK369796 Dihydrochloride
    		Inhibitor 99.56%
    GSK369796 Dihydrochloride is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.
    GSK369796 Dihydrochloride
  • HY-N2377
    Allosecurinine
    		Inhibitor 99.61%
    Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus .
    Allosecurinine
  • HY-120338
    RYL-552
    		Inhibitor 98.63%
    RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor.
    RYL-552
Parasite Isoform Comparison

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